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Avoid Vitamin D3 Deficiency Though definitions of vitamin D deficiency can vary, experts agree that it has nearly reached epidemic status

Fibroblast-like synoviocytes (FLSs) contribute to pannus formation and matrix degradation through MMP-1 and MMP-3, with expression levels 5 - 10 times higher in RA synovium (Figure 1) (14)

(2) Investigation of citrulline supplementation, either in its pure form or derived from natural sources (e.g., watermelon)

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Ethical approval All aspects of this study were approved by the Research Ethics Committee of Chongqing Medical University (reference number: 2022056)

Investigation of cathinone analogs targeting human dopamine transporter using molecular modeling