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It plays a crucial role in neutralizing free radicals, reducing inflammation, and supporting the immune system

Cunha GR, Hayward SW, Wang YZ

Parallel to the findings from rat liver mitochondria, it has been recently reported that mitochondrial cholesterol enrichment, resulting in mGSH depletion, is a major mechanism of anthrax lethal toxin-induced macrophage cell death (Ha et al., 2012)

Glutathione disulfide (GSSG) is thereby generated

doi: 10.3389/fphar.2023.1147414 Received 18 January 2023 Accepted 22 February 2023 Published 02 March 2023 Volume 14 - 2023 Edited by Zhihao Liu, Dalian Medical University, China Reviewed by Ral Gonzalez Ojeda, University of Galway, Ireland Hang Liu, University of California, Los Angeles, United States Updates Copyright 2023 Pei, Pan, Wei and Hua

In a study done in 15 patients with PD, 200 mg of GSH was given intranasally and showed that GSH levels did not only raise, but the levels remained high even 1 hour after administration