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Cell (2016) 167:829842.e13.10.1016/j.cell.2016.09.031 35 MurphyMP

The C-CRD of Yap1 consists of a leucine-rich export signal (NES) and two cysteine-rich domains (CRD) positioned at the N- and C-termini

[268] It is envisaged that the composition of the invention might comprise, in addition to the polypeptide of the invention defined herein, further biologically active agents, depending on the intended use of the composition

These include frequent or prolonged exposure to sunlight, genetic predisposition, and hormonal fluctuations, especially those related to pregnancy or hormonal therapies, all of which can increase melanin production

Breed 41, 25

BRD4 negatively regulates ferroptosis by activating xCT, repairing the DNA, and inducing senescence-associated secretory phenotype (SASP), a ferroptosis resistant cellular program (Tasdemir et al., 2016