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Dutasteride (brand name Avodart) is a 5-alpha reductase inhibitor originally approved by the FDA for benign prostatic hyperplasia, an enlarged prostate condition

The second pathway of Nrf2 activation involves degradation of KEAP1 through the autophagy apparatus

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An increase in nave B cells (or their recruitment) together with expansion of activated memory CD4+ T cells may reflect ongoing antigenic stimulation (for example, persistent tumor antigen exposure or chronic inflammation) and a degree of immune activation