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The extrinsic factor is now known as vitamin B12 (cobalamin) and provides an effective therapy for Pernicious Anaemia

India's National Family Health Survey (NFHS-5) found that 57% of women of reproductive age are anaemic, and vitamin C is one of the most effective ways to improve absorption of the non-heme iron found in dal, spinach, and other plant sources

In another rat experiment, vitamin E has been shown to control hyperglycemia and lower glycated hemoglobin, and HbA1c, by suppressing the oxidative stress level (Ihara et al

Vegetarians, vegans, older adults, and people with conditions that affect nutrient absorption (like Crohn's disease or pernicious anemia) are at higher risk of Vitamin B12 deficiency

Clinical response rates in clinical trials have ranged from 30 to 60% over the first eight to 12 weeks, with endoscopic remission usually slower in onset

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