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The enterotrophic peptide hormone glucagon-like peptide 2 (GLP-2) was shown to abrogate OS and improve intestinal antioxidant capacity by reducing LPS-induced increases in intestinal IL-1 and oxidized glutathione levels (267) and increasing intestinal SOD activity and reduced-glutathione levels (268, 269) ( Supplementary Table 1 )

Recent studies confirm the presence of ferroptosis in HS and highlight key targets regulating this process (Figures 2C, D

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It also shows a very promising characteristic in terms of overcoming any memory and motor dysfunction

210 min 95% buffer B (linearly increasing)

To confirm this, immunostaining revealed that ATG5 and LC3B were present throughout the corpus callosum and in spinal cord white matter, as well as in myelinating co-cultures where ATG5 colocalized in myelin wrapped axon segments