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Ions are separated in the first mass analyzer (MS1), enter the collision cell and undergo fragmentation, resulting in generation of ions called product ions which are separated in the second mass analyzer (MS2) and detected

1: Sikiric P, Barisic I, Udovicic M, Lovric Bencic M, Balenovic D, Strinic D, Posilovic GZ, Uzun S, Vranes H, Krezic I, Lozic M, Stambolija V, Premuzic Mestrovic I, Oreskovic LB, Kalogjera L, Strbe S, Sikiric S, Tomic L, Stupnisek M, Kordic M, Tvrdeic A, Seiwerth S, Boban Blagaic A, Skrtic A

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When Vero (African green monkey kidney) cells were exposed to aspartame (0.5 mM [145 g/mL]) for 24 hours, MDA production was not different from that in the controls (Baudrimont et al., 1997