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of this final rule with comment period, CMS is finalizing, with modification, that beginning January 1, 2026, if a hospital's payer specific negotiated amount is based on an algorithm or percentage, the hospital would be required to describe the percentage or algorithm and report a new data element, the median allowed amount, instead of the estimated allowed amount, and that the median allowed amount is defined as the median of the total allowed amounts the hospital has historically received from a third-party payer for an item or service for a time period no less than 12 months and no longer than 15 months prior to the date the MRF is posted

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[3] This matters enormously for interpretation: a result obtained with CagriSema describes cagrilintide plus a potent GLP-1 analog, and cannot be read as the effect of cagrilintide by itself