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Description

Antioxidants , 12 (4), 782

The composition of the culture medium was based on the conditions investigated in the flask experiments above, but some components were prepared at somewhat higher concentrations (see Methods), taking into consideration the aim for a higher cell density in this culture system

Both accumulated succinate and fumarate are potent inhibitors of prolyl 4-hydroxylases (PHDs)

enhancing data sharing between trials

Clinical studies have confirmed that the number of Ki67 + and phosphorylated STAT3 + hepatocytes and cholangiocytes in patients with alcoholic cirrhosis is significantly decreased, indicating that hepatocyte proliferation is inhibited (Horiguchi et al., 2007)