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The cGAS-STING pathway-dependent sensing of mitochondrial DNA mediates ocular surface inflammation

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Furthermore, TMAO promotes endoplasmic reticulum stress responses within podocyte cellular compartments via IRE1 and PERK pathway activation architectures, culminating in amplified production of inflammatory cytokine arsenals and accelerated apoptotic cell death trajectories (Pan et al., 2023)

Cordeiro S, Silva B, Martins AM, Ribeiro HM, Gonalves L, Marto J

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C., O'Neil, B