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Previous studies have revealed that small molecules that use chloroacetamido groups as electrophilic moieties may be effective covalent GPX4 inhibitors (72,73)

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10.1016/j.bbalip.2016.03.014 15

Without getting into the incredibly detailed science describing these tests, it has been accepted that multi-use vials can only be used safely for 28 days after the first puncture