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Clinical trial results Sarcoidosis-associated small fiber neuropathy: In a blinded, placebo-controlled trial, 28 days of daily subcutaneous ARA-290 administration in patients with documented small nerve fiber loss produced significant improvements

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The peptide influences laminin-5 (LN-5) expression in a temporally sophisticated mannerinitially inhibiting LN-5 to promote cellular proliferation and differentiation, then upregulating LN-5 expression during middle and late healing stages to improve the matrix environment and promote epidermal cell migration

351(c)], in that its strength differs from, or its purity or quality falls below, that which it purports or is represented to possess

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