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After heating, 20 mL of distilled water was added

Chobanian AV, Bakris GL, Black HR, et al

Once the xenograft tumors for the study of 2DG or BPTES treatment were established (when the tumor volume was ~50100 mm 3 ), the mice were randomly divided into six groups ( n = 5 mice per group) and treated with saline buffer (10% DMSO), 2DG (500 mg/kg/day) or BPTES (12.5 mg/kg/day), each with or without TRAIL (5 g/kg/day), via intraperitoneal injection three times a week for 33 days

Ann NeurolAnn Neurol 8 (1): 1-31

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However, the pharmacokinetic interaction of NS with conventional drugs raises some concerns which need addressing