glutathione intravenous dose Glutathione Injections: Benefits, Dosage, and

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An orally available small-molecule inhibitor of c-met, PF-2341066, exhibits Cytoreductive antitumor efficacy through Antiproliferative and Antiangiogenic mechanisms

Vanittanakom, N., Cooper, C

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Biomaterials 2013;34:2773-86

These amenable properties demonstrated for the small molecules led us to conduct a proof-of-concept in vivo study in diet-induced obese mice to test the hypothesis that the most potent inhibitor when administered systemically, would reverse obesity by causing substantial loss of body weight and adiposity without causing any observable adverse effects