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In MCF7 breast cancer cells, as well as PC3 prostate cancer cells, deprivation of most amino acids but glycine reduced cell number to approximately the same extent, whereas methionine deprivation led to the most dramatic reduction in cell number (Tang et al., 2015)

5.4 Fibroblast activation and ECM remodeling Ferroptosisassociated inflammation activates myofibroblasts, which secrete matricellular proteins such as periostin and fibronectin

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Cartilage-targeting peptide-modified dual-drug delivery nanoplatform with NIR laser response for osteoarthritis therapy

Signaling pathways in cancer metabolism: mechanisms and therapeutic targets

135 AIM2 deficiency, another sensor involved in inflammasome activation, enhances APAP-induced inflammation and acute liver injury in aged mice by promoting oxidative stress and phosphorylation of JNK