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Journal of orthopaedic research : official publication of the Orthopaedic Research Society , 24 (5), 982-9

Growth Hormone & IGF Research: Official Journal of the Growth Hormone Research Society and the International IGF Research Society, 10 Suppl B, S57S62

Theyre promising for a few reasons

Almost no source treats them separately which is exactly why so much conflicting information exists on this topic

Mild reactions may resolve by discontinuing supplements, while severe symptoms may require medical intervention, such as supportive care or medication