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In patients who do not respond to a TNF inhibitor or in whom this response wanes, there are observational data to suggest that a switch to another agent in the class can be successful

(1984) using a one-compartment kinetic model was approximately 80 min

[DOI] [PubMed] [Google Scholar] 134.Hogan, K

It does not directly stimulate fibroblast proliferation under normal culture conditions, but substantially increases fibroblast survival under hydrogen peroxide-induced oxidative stress acting as a cytoprotective enhancer of the endogenous repair response rather than a direct mitogenic agent

Hwang, K

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