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The transfer of Zn at the cellular level and among tissues occurs via specific Zn-irk like receptors- ZIP, Solute Carrier family 39A (SLC39A) and receptors Zn transporters (ZnT) (SLC30A), the role of which will be expanded later in this review (Figure 1)

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Conversely, adrenergic drugs bind to extracellular loops of opioid receptors, enhancing their activity