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In MPTP-treated neuronal cultures, paeoniflorin restored cell viability, normalized elevated intracellular Ca 2+ , and decreased apoptosis markers relative to untreated controls (38)

doi: 10.1016/j.immuni.2018.03.013 172 MaLGengJChenWQinMWangLZengY

Polyamine acetylation modulates polyamine metabolic flux, a prelude to broader metabolic consequences

The following discussion will examine the sophisticated mechanisms underlying aging and inflammation , colloquially termed inflammaging . We will explore why traditional approaches to fatigue and metabolic dysfunction often failspecifically because they neglect the degradation of cell-to-cell communication

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Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, et al