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Additionally, IF downregulated the expression of AQP4-M1 and histone deacetylase 3, reduced the AQP4-M1/M23 ratio, and increased miR-130a expression in the cortical region of APP/PS1 mice

Brain energy metabolism Insulin signaling Type 2 diabetes mellitus (T2DM) is another risk factor for cognitive decline and late-onset AD

Furthermore, the newly developed xanthonic compounds were found to have a relatively low toxicity margin

Some research suggests glutathione increases DOPA levels, potentially redirecting melanin precursors away from pigment production pathways

Functionally, HEK293- SLC13A3 cells had a significant increase in the uptake activity of 14 C-succinate compared to HEK293- EV cells (Supplementary Fig

Z90.3 is a status code, not a primary diagnosis