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In the area of antibody engineering, the therapeutic potential of novel conjugated half-life extended nano-BiKEs (Bispecific Killer-cell Engagers) was evaluated

Chauhan et al, 55 James et al, 56 and Al-Gadani et al 57 reported higher LPO in the blood of children with autism as compared to their developmentally normal, non-autistic siblings

Antioxidant therapy: current status and future prospects

Primary endpoint: GSH concentration in venous umbilical cord blood erythrocyte in response to NAC supplementation GSH concentrations in venous cord blood did not differ between NAC and placebo arms, whether FAS ( P 0.38) or PP ( P 1.0) populations were considered

2.3.3 Metabolite analysis of BPC157 We analyzed the metabolites of [ 3 H]BPC157 in rat plasma, bile, urine, and feces using the samples collected during the aforementioned extraction and plasma pharmacokinetic studies

4.1 Enzymatic mechanisms 4.1.1 The glutathione (GSH)-GPX4 axis Ferroptosis is characterized by the hallmark feature of intracellular lipid peroxide accumulation, with the glutathione-glutathione peroxidase 4 (GSH-GPX4) axis playing a pivotal role in suppressing lipid peroxidation