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The peptides ability to stimulate connective tissue accumulation and collagen synthesis has been demonstrated in experimental wound models 5

In the AMY 3 R consensus maps, density allows potential modelling of an alternate rotamers of F23 Cagri in antiparallel with Y146 1.37 (Supplementary Fig

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[7] Likewise, the investigational drug fasoracetam (in the same class as piracetam) has been studied in adolescents with ADHD and certain genetic traits early results showed improvements on ADHD symptom scales

To interrogate the potential effect of the lipidation on the Cagri-bound structures, we also determined structures of the CTR and AMY 1 R bound to a Cagri analogue lacking the N-terminal lipidation (CagriBB)