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Additive anti-inflammatory effects of corticosteroids and phosphodiesterase-4 inhibitors in COPD CD8 cells

Translating them into effective strategies for the prevention or treatment of IBD remains a promising scientific hypothesis that urgently requires direct validation of efficacy and specific mechanisms in IBD animal models and clinical studies

Swanson JA, Antonoff MB , Martodem DL, Schmitz CC, DCunha J, Maddaus MA

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These factors collectively drive intestinal inflammation, fibrosis, impaired bacterial clearance, and compromised epithelial barrier function, emphasizing autophagy in CD management

Ecotoxicol Environ Saf 180:575587