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The endocannabinoids produced from arachidonic acid (AA) include anandamide and 2-arachidonoylglycerol, whereas those from omega-3 PUFAs include docosahexaenoyl ethanolamide (from DHA) and oleylethanolamide and palmitoylethanolamide (from EPA) (78)

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Animal research shows ALC supplements can create quick and lasting antidepressant-like effects

But high levels released during stress flood low-affinity receptors that actively impair the PFC which is why "mild, uncontrollable stress can cause a rapid and dramatic loss of prefrontal cognitive abilities," and why prolonged stress remodels prefrontal dendrites.5 This is not a metaphor for being frazzled