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Benefits : Direct application to affected areas

Neurobiol Dis 146:105120

In addition, mitochondria lack more advanced repair pathways, such as nucleotide excision repair and homologous recombination, which makes mtDNA particularly susceptible to the accumulation of mutations [35], which leads to a higher rate of damaged mtDNA in mitochondria and further aggravates oocyte damage

Both oral and intramuscular B12 are compatible options

doi: 10.1016/j.biopsych.2008.01.008

TCF induced bending facilitates the architectural framework for large chromatin regions to be organized together to stimulate a burst of chromatin reorganization dependent on -catenin bound HAT (CBP) activity (Heintzman et al., 2007