male broiler chickens glutathione Novel role and mechanism of peroxidase-4 in nutritional pancreatic atrophy of chicks induced by dietary selenium deficiency Oxidative stress in poultry production

Nat Genet 47(12):1426-34, 2015

Conversion of 5-OP to Glu by 5-Oxoprolinase The 5-OP that is the result of CHAC-catalyzed glutathione cleavage is converted to Glu by 5-oxoprolinase (OPLAH) in an ATP-dependent manner [122]

738 Abnormal xCT function causes GSH depletion and sufficiently triggers ferroptosis

This response involves three primary pathways: PKR-like ER kinase (PERK), inositol-requiring enzyme 1 alpha (IRE1), and activating transcription factor 6 (ATF6), all of which are activated under conditions of ER stress [49]

Transgenic tomatoes showing higher glutathione peroxydase antioxidant activity are more resistant to an abiotic stress but more susceptible to biotic stresses

For example, Angong Niuhuang Wan inhibits the accumulation of ROS and Fe 2+ and improves mitochondrial dysfunction and BBB structural integrity by activating the PPAR/AKT/GPX4 pathway, thereby enhancing neurological function in rats with ischemic stroke and reducing cerebral infarction volume