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Since GSH synthesis depends on the availability of cysteine that in the cell is derived from the reduction of cellular cystine imported into the cells through the xc- system, a cystine-glutamate exchanger,[33] we subsequently examined the expression of components of the xc- system and found upregulated expression of transcripts for SLC3A2 and SLC7A11 in stimulated CD4 + T cells (Suppl

Peripheral neuropathy is the most common and represents the main cause of altered gait, neuropathic pain, foot ulceration, and amputation [58]

During the second week, thickening of the renal corpuscles, increased vascular wall thickness, and a reticulated collagen staining pattern in the medulla were noted

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