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Short-chain enoyl-CoA hydratase mediates histone crotonylation and contributes to cardiac homeostasis

The differential equations provide the temporal variations in the concentration of each specie participating in above reaction network i.e., R 1 -R 12

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J Clin Rheumatol, 2009

She notes a roughly 15% overall complication rate and only about a 2% adrenal necrosis rate with trilostane, with more adverse effects seen at higher doses