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Ferraz et al

Dermatologic Surgery, 51(2), 198-207

VDAC1 balances mitophagy and apoptosis in leafhopper upon arbovirus infection

This triad promotes the release of pro-inflammatory cytokines and induces a predominant Th1-mediated immune response characteristic of Hashimotos thyroiditis (HT)

Given that GSSG was significantly accumulated in the A2ARi-treated activated CD8 + T cells (Figure 3H), we hypothesized that the T cell ferroptosis induced by A2ARi could be due to the enhanced GSH usage and subsequent increased GSSG accumulation