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J Appl Physiol (1985) 120 , 657658, doi:10.1152/japplphysiol.00749.2015 (2016)

Semaglutide (Wegovy) and tirzepatide (Mounjaro) and the investigational combination of semaglutide and an amylin analogue (CagriSema) have shown impressive results in studies of people with obesity

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This is the central idea of the research by David Sinclair (Harvard), Shin-ichiro Imai (Washington University) and other NAD+ apostles in the longevity field