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261 However, normal lysosomal function and the sequestration of cytosolic components during autophagy depend heavily on adequate ATP levels

Furthermore, Fernndez et al., 2019 examined the cytotoxic effects of 10 nm and 60 nm silver nanoparticles (AgNPs) in hepatic (HepG2) cells, a model chosen due to the livers known tendency to accumulate AgNPs

In this context, the present work evaluated the applicability of the commercially available upper MucilAir-HF and lower EpiAlveolar human lung models to be used as in vitro systems within a NAM toolbox to identify the bioactivity (i.e., in vitro PoD derivation) and risk of materials that may reach the respiratory tract and induce lung toxicity

[CrossRef] [Google Scholar] Psoriatic arthritis