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Pathway-level effects

The cancer-fighting ability of olive oil is connected to the antioxidant nature of its phenolic and polyphenolic constituents, which help in neutralizing free radicals and reactive oxygen species

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l-ornithine phenylacetate attenuates increased arterial and extracellular brain ammonia and prevents intracranial hypertension in pigs with acute liver failure

For instance, it remains unclear how ferroptosis in neutrophils [e.g., GPX4 deficiency-induced iron release (216)] directly modulates T/B-cell differentiation or macrophage activation, or whether DAMPs released by ferroptotic immune cells propagate ferroptosis in renal parenchymal cells (e.g., tubular epithelial cells)