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The infected T cells co-expressed Thy1.1, allowing us to gate on the Thy1.1 + subset for the precise examination of vector and Gclc-OE T cells

These residues are highlighted in the structural alignments (Figure 2)

Consistent with this hypothesis, cultured cells showed that MeHg induces a selenium-deficient-like condition, which affects GPx1 synthesis through a posttranscriptional effect (Usuki et al., 2010)

The imbalance in the ferroptosis defense system Ferroptosis can be suppressed by GPX4-dependent and GPX-independent methods

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There is still a gap in existing research in the field, necessitating well-designed, robust, multicenter clinical trials, with sensitive endpoints and standardized protocols to facilitate the diagnosis of DPN via a simple and effective algorithm and to track progression of disease and treatment response