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This study also suggests that these compounds have a promising impact on lipid metabolism, suggesting their significance in addressing obesity-related metabolic disorders

Figure 3 Mitochondria and lupus nephritis The kidney is one of the most energy-consuming organs in human body and the mostly attacked organ in lupus ( Dysfunction of podocytes with abnormal permeability and viability and aggravated podocytes apoptosis by pathogenic IgG and IFN- have been found in LN patients and lupus mice, which could be partially restored by activation of autophagy via mTORC1 inhibition ( via Mfn1 and Drp1 expression

Astrocytes, key modulators of neuroinflammation, congregate around A plaques, as described in both human and mouse models

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