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While there are multiple causes of cardiovascular disease, most boil down to the development of atherosclerosis , or hardening of the arteries. Atherosclerosis is promoted by factors such as oxidation of LDL cholesterol, accumulation of that oxidized fat in arterial walls, and damage to the endothelium, which is the thin layer of cells lining those arterial walls

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Headache was notably identified as the predominant adverse effect associated with tranilast

Molecular cellular mechanisms of peptide regulation of melatonin synthesis in pinealocyte culture