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Description

Sun et al., 2010

A Herx reaction may also amplify mast cell activation, leading to MCAS flare-ups

Given that 6-HI has functions beyond RTA, this compound may serve as a scaffold for synthesizing additional lead compounds that could exhibit improved pharmacokinetic and pharmacodynamic properties

Research output: Contribution to journal Article peer-review

All cited studies are conducted in cellular or rodent systems consistent with RUO classification

However, no significant difference in cell viability was found, suggesting that ACE did not induce ferroptosis by activating the enzymatic activity of HO-1 (Supplementary Fig