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Approach Phase 2b trial arm Duration 24 weeks Review Point Week 12 and 24 Notes METAOD006 (OPTIONS) used 24 weeks at oral doses 0.25, 0.5, or 1 mg/day in 502 obese adults

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Brains were cut (30 m thick sections) in the frontal plane using a freezing microtome

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10.1016/j.intimp.2021.108175 52 XuZ.ZhangQ.DingC.WenF.SunF.LiuY.et al (2023)

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