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Garg R, Faderl S, Garcia-Manero G, Cortes J, Koller C, Huang X, York S, Pierce S, Brandt M, Beran M, Borthakur G , Kantarjian H, Ravandi F

V.BowmanJ.LeachA

It is known that insulin/AKT signaling augments the responsiveness of cells to TGF- exposure by increasing the trafficking of TGF- receptors to the cell surface as demonstrated in mouse embryonic fibroblasts and epithelial cells [35]

Afterwards, relative staining intensities of MBP, GFAP and IBA-1 were semi-quantified in binary converted images, and the results were transformed into percentage area values

This peptide has been suggested to exhibit its potential primarily on fibroblasts, responsible for maintaining and growing the extracellular matrix (ECM) components surrounding the cells