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Upcoming trials of TIL therapy in breast cancer include a phase II trial (NCT04111510) is investigating LN-145 TIL therapy in mTNBC, a phase I/II (NCT05451784) trial of PD-L1+ TILs in TNBC, a phase Ib (NCT05576077) study of TBio4101 with pembrolizumab in solid tumors including breast cancer, and a phase II (NCT03449108) trial of LN-145-S1 with ICI in metastatic TNBC

The SVM classifier achieved an area under the curve (AUC) of 0.953, accuracy of 0.884, sensitivity of 0.963, and specificity of 0.648 for detecting LAS