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Expression and regulation of hif-1alpha in macrophages under inflammatory conditions

Similar to ferroptosis, cuproptosis leads to notable alterations in mitochondrial structure, such as shrinkage and membrane rupture

Fibrosis has potentially lethal consequences, and lacks effective treatment 1,2,3,4,5,6,7

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[DOI] [PMC free article] [PubMed] [Google Scholar] 1204.Kudinov AE, et al

the C-2 of the glycerol backbone of phophoglycerides is generally esterified to a polyunsaturated fatty acyl chain such as arachidonate, and the C-2 ester may be acted on by phospholipase A 2 (PLA 2 ) thereby releasing free arachidonate