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Injury or trauma : Following trauma to your thyroid (such as neck injury, thyroid cancer treatment, or surgery), your thyroid gland may get damaged, leading to hypothyroidism

There, hepatocytes conjugate bilirubin with glucuronic acid (via UGT1A1) to form water-soluble conjugated (direct) bilirubin, which is excreted into bile and ultimately eliminated in stool as urobilinogen (StatPearls Jaundice)

Dikmen S S, Corrigan J D, Levin H S, Machamer J, Stiers W, Weisskopf M G (2009) Cognitive outcome following traumatic brain injury

Folate (folic acid, Vitamin B-9), often recommended during pregnancy, is also largely attributed to brain development and later-in-life cognitive function