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High levels of IGF-1 and GH signal back to the hypothalamus and pituitary to pump the brakes on GHRH and GH release

On strength testing, he showed antigravity strength in the proximal LLE, severe continued paresis of the distal LLE, and 4/5 on the right lower extremity, although he still complained of decreased sensation bilaterally in his legs

Science 360:eaaq1723

10.1016/j.numecd.2021.04.006 77

4B), indicating an active bile acid dehydroxylation in these mice

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