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A new derivate of DOX, 4-acetyl-2-nitro-benzenesulfonyl doxorubicin (ANS-DOX) was synthesized and shown to be converted into DOX by MGST1 and GSTA1-1, whereas no activity was observed for GSTP1-1 128

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However, anaphase chromosome-segregation errors increased dramatically, from 4.4% in control cells to 38.3% in H2B-Sororin-CTR-GFP cells (Fig

Secondary plots revealed a type- and charge-dependent decrease of the true k cat value for the E170X mutants

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