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1d are available at the following PDB accession codes: 1EGO, 1GRX, 1QFN and 1EGR

& Specian, R

aureus produces alpha-toxin, a pore-forming toxin that inserts itself into the membranes of host cells, causing cell lysis and contributing to tissue destruction

This suboptimal microbiome aggravates symptoms in those with the MTHFR 677T genotype (Regland et al., 2015

Overall, these three OSMs play a crucial role in the pathogenesis and progression of IBD and have been suggested to serve as potential diagnostic, differential, progression, and prognostic markers in the disease