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Another study showed that copper ions play important roles in the early stages and development of cancer 14 , and HT interacts with copper to reduce the invasiveness of MDA-MB-231, MDA-MB-468 and SUM159 cells by decreasing copper ion levels 15

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Studies have identified CYP450 enzymes as a key mechanism through which dietary flavonoids modify the bioavailability of therapeutic drugs

Anti-tumor angiogenesis increases the normalization of blood vessels, inhibits tumor hypoxia and the immunosuppressive TME, increases the effective drug concentrations in tumors, and enhances drug efficacy

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It is indicated that the transfer of specific immunomodulating components, such as bioactive proteins, from mother to infant through human milk contributes to this protective effect