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Conditions such as systemic lupus erythematosus (SLE) are not included, despite their potential to cause pre-senile dementia through mechanisms like autoimmune antibodies targeting sodium channels on glutamatergic neurons [495]

Avoid combining vitamin C with: AHAs/BHAs : This includes alpha hydroxy, glycolic, lactic, beta hydroxy and salicylic acids

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Further, homocysteine inhibits the expression and synthesis of antioxidant enzymes and radical scavengers, which results in increased cellular apoptosis in response to oxidative stress (26, 47)

Cancer Lett 320:171179