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It minimizes systemic toxicity to the greatest extent and provides an ideal strategy for achieving localized, long-acting treatment

In another study, apatinib also improved the levels of T helper 1 (Th1) and T helper 2 (Th2)-like cytokines (107)

In endothelial cell models, BPC-157 enhanced ERK1/2 phosphorylation in a dose-dependent manner, increasing cellular proliferation, migration, and vascular tube formation via downstream transcription factors c-Fos, c-Jun, and EGR-1