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27 observed reduced nitrate and antioxidant enzyme levels (SOD and catalase) in DOCA-salt rats

Furthermore, our preliminary experiment revealed that long-term (12 weeks) supplementation of glutathione (50 mg/kg body weight) in mice did not significantly increase liver glutathione levels compared to than in controls, indicating that oral administration of glutathione does not significantly affect the glutathione levels in the liver, when sufficient amounts of glutathione can be synthesized

Liposomes: Liposomes have high biocompatibility and degradability, and their surfaces can be chemically modified to enhance targeting

10.1038/onc.2015.20 Oncogene 50 GuiY.YeganehM.RamanathanS.LeblancC.PomerleauV.FerbeyreG.et al (2011)