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Oxidative stress causes airflow obstruction that leads to tissue hypoxia and could stimulate an inflammatory response [68]

Some regenerative therapies are now available for chondrocytes but they are expensive

Relative Slc19a2 mRNA levels were significantly increased by 1.34-fold in mice supplemented with thiamine for 7 days compared with thiamine-depleted mice, but did not differ significantly from mice receiving AT for 7 days