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Sies H, Cadenas E (1985) Oxidative stress: damage to intact cells and organs

331 Several indole derivatives, including indole-3-ethanol, indole-3-pyruvate, and indole-3-aldehyde, maintain the integrity of the apical junctional complex and improve intestinal barrier integrity by activating the epithelial AHR (Fig

Compounds like flavonoids, alkaloids, and terpenoids work in a variety of ways, such as boosting insulin sensitivity and secretion, blocking enzymes that break down carbohydrates, increasing glucose absorption, lowering oxidative stress, and maintaining pancreatic -cell function

This activation can further contribute to the heightened ROS production, alongside glucose auto-oxidation and the formation of advanced glycation end products (AGEs) (Mailloux 2018)

Eat your fruit and veggies, get a decent amount of sleep and look after your brain

Our research demonstrates that TLK2 activation by calcium overload appears to be a pivotal step in the progression of PD